Broad Objectives:

1. To provide continued support for our state-of-the-art laboratory-based training in our established focus areas (CF immune dysfunction, microbial pathogenesis, the interface of macrophages and neutrophils with CF pathogens, and CF airway epithelial physiology).
2. To enhance training in our emerging focus areas (Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modifier effects on immune cell function, progenitor cell biology and therapy, CFTR channel function and dysfunction, and therapeutics aimed at managing infection and inflammation).
3. To make available partial financial stipend and tuition support (cost share agreement) for one graduate student and one post-doctoral trainee. 
4. To provide potential biomedical research career trainees with a strong foundation in basic sciences and the direct lab experience needed to conduct research in our established and emerging focus areas.
5. To support our core C3 trainee enhancement programs.

Daniel Wozniak, PhD

Co-Director, C3 Training Program

Dr. Wozniak is a nationally recognized leader in CF training, serving as a standing member of the Cystic Fibrosis Foundation Research and Research Training Committee since 2008. He has trained 16 PhD students and 7 postdoctoral fellows, each having established independent careers in biomedical sciences.​

Stephen Kirkby​, MD

Co-Director, C3 Training Program

Dr. Kirkby is currently the Associate Program Director of the Nationwide Children's Hospital Pediatric Pulmonary Fellowship Program. He is an adult and pediatric pulmonary physician with expertise in the care of people with CF and lung transplant recipients. Dr. Kirkby’s focus on CF includes his work on educating both pediatric and adult pulmonary fellows in addition to the active role he maintains in clinical and translational CF research.

C3 Training Programs:

​To achieve our training objectives, we have several C3 trainee enhancement programs. All trainees affiliated with C3 mentors those supported by C3 fellowships, and trainees affiliated with OSU/NCH that express an interest may participate.

Semester graduate level course “Cystic Fibrosis Pathophysiology”
C3 CF externships:

• Columbus Public Health: for trainees interested in public health and policy
• Center of Science and Industry: for those interested in science education
• Battelle Memorial Institute: for trainees interested in a career in industry science
• OSU or NCH Technology Commercialization Office: for those interested in commercialization and legal aspects of research findings
• OSU/NCH clinical microbiology laboratory: for trainees interested in clinical microbiology/ immunology.
• Central Ohio Chapter Cystic Fibrosis Foundation: for trainees interested in local CF activities including fundraising, networking, volunteer opportunities, and parent/patient advocacy
• C3 RDP translational meetings

Bench to bedside training series (quarterly)
CF Literature Reviews, Scholarly Presentations, and TED-Talks
Basic Scientist CF Clinical Exposure Program
The Clinical Scholar Plan
Plan for Pathway to Independence

Current & Former C3 Trainees

C3 Trainee (C3 Mentor) C3 Project Title

Jack Wellmerling

(Estelle Cormet-Boyaka)

​A novel approach to improving mucociliary clearance in CF

Kaitlin Hamilton

​(Amal Amer)

Mitochondrial dysfunction in CF macrophages

Katarzyna Danis-Włodarczyk

(Matthew Sullivan)

Killer cocktails, introducing phage therapy in CF treatment

Frank H. Robledo Avila

​(Daniel Wozniak)

Expression and function of CFTR chloride channel in neutrophils

​Landon Locke

(​Santiago Partida-Sanchez)

Targeted imaging of Pseudomonas aeruginosa biofilms

​Kaitlin Hamilton

(Amal Amer)

Identification of mitochondrial dysfunction in CF macrophages

Yiwei Liu

(Daniel Wozniak)

The role of P. aeruginosa Psl during in vitro and in vivo interactions with S. aureus